
I offer CaHA treatment in Singapore in three forms. Undiluted CaHA with lidocaine is used for cheek, chin and jawline contour. Diluted CaHA is used for skin tightening of the face, neck, décolletage, hands and arms. Diluted CaHA in sequence with HIFU is used for lower face and neck laxity. CaHA for contour is $1,400 per syringe and diluted CaHA is $1,800 per session, before GST. Performed by Dr Gerard Ee, MBBS (UK), MRCS (Edinburgh), PGDip Practical Dermatology (Cardiff).
CaHA treatment at a glance
| What it does | Undiluted, it lifts and contours the cheeks, chin and jawline. Diluted, it firms lax skin by stimulating new collagen and elastin. |
| Product | Calcium hydroxylapatite (CaHA) microspheres in a gel, with lidocaine |
| Price | $1,400 per syringe. Diluted CaHA $1,800 per session or $3,000 for 2 sessions, before GST. |
| Sessions | Contour usually one session. Skin tightening usually 2 sessions, 4 to 8 weeks apart. |
| Time | 30 to 45 minutes |
| Downtime | Swelling and mild bruising for a few days |
| Results last | 12 to 18 months on average |
The evidence behind each use is set out in my CaHA filler in Singapore review.
Who suits CaHA treatment
A jawline that has lost its edge, or a short or receding chin, is given structure with undiluted CaHA placed close to the bone.
Flattened cheeks that need lift and projection, rather than soft volume, are treated with undiluted CaHA.
Thin, crepey skin on the neck, décolletage, hands or arms is firmed with diluted CaHA, which adds no volume.
Early jowls and a softening lower face are treated with HIFU first and diluted CaHA six weeks later.
CaHA jawline, cheek and chin treatment

Undiluted CaHA is placed deep, close to the bone, where the firm gel lifts the overlying tissue to define the jawline, lengthen or project the chin and restore cheek projection. The CaHA I use for contour contains lidocaine, a local anaesthetic, which makes the injection comfortable without separate numbing. Most patients need one to two syringes. The result is visible immediately and firms further over the following two to three months as new collagen forms around the microspheres.
Diluted CaHA skin tightening for the face, neck, décolletage, hands and arms

For lax or crepey skin, CaHA is diluted with saline and spread in a thin layer under the skin with a fine blunt cannula, which passes beneath the skin from a single entry point and lowers the risk of bruising. The diluted gel adds no volume. Skin firmness and thickness improve gradually over three months. I usually plan two sessions four to eight weeks apart. Use on the neck, décolletage, hands and arms is off-label, and I explain this before treatment. The 2018 global consensus notes that in Asian skin a 1 to 1 dilution is needed to get a response in the neck, décolletage, upper arms and legs, which is why I decide the dilution at assessment rather than using one ratio for everyone.
What happens on the day of CaHA treatment

The consultation assesses skin thickness, facial structure and any previous filler, because CaHA cannot be dissolved and the plan has to be correct before the first injection. Photographs are taken and the treatment areas are marked. Numbing cream is applied for diluted treatment, whereas contour treatment relies on the lidocaine already in the product. Injection by needle or cannula takes thirty to forty-five minutes. A review follows at two to four weeks.
CaHA downtime and aftercare

Swelling and mild bruising settle within a few days. Massage of the treated area should be avoided unless I advise it, because pressure can displace the gel before the surrounding tissue holds it in place, and strenuous exercise, saunas and facials are avoided for 48 hours. Because CaHA cannot be dissolved, I ask patients to contact me early if a lump or unusual pain appears, as an early nodule is simpler to treat than an established one.
CaHA with HIFU for lower face and neck laxity

For a softening jawline, early jowls or a loose neck, I combine HIFU with diluted CaHA, using Tightan 2 for a deeper lift or Sygmalift for gentler fractional HIFU. HIFU is performed first and diluted CaHA six weeks later, the sequence that produced the greatest gain in new elastin in a randomised study. HIFU tightens the deeper connective tissue layer, and CaHA placed six weeks later firms the skin above it while the repair response to the heat is still active. In the randomised study, the HIFU-first group showed a 143% relative increase in elastin coverage against 63% in the reverse-order group, and felt they looked about 4 years younger at 120 days.
CaHA price in Singapore

| Treatment | Price before GST |
|---|---|
| CaHA with lidocaine for jawline, cheek or chin, per syringe | $1,400 |
| Diluted CaHA skin tightening, per session | $1,800 |
| Diluted CaHA skin tightening, 2 sessions | $3,000 |
| CaHA with Tightan 2 HIFU | Tightan 2 $3,500 plus diluted CaHA $1,800 |
| CaHA with Sygmalift HIFU | Sygmalift $1,200 plus diluted CaHA $1,800 |
CaHA for the nose is priced on my CaHA nose filler page. The 2019 consensus suggests one maintenance session 12 to 18 months after the initial course, which is the basis for the two-session plan and the maintenance interval above.
Who CaHA treatment does not suit

CaHA is not used in the lips, around the eyes or between the brows, where thin, mobile skin raises the risk of visible lumps. In the largest published safety review of “Radiesse®, or calcium hydroxylapatite (CaHA)”, nodules were the main adverse event, with a 9.4% adverse event rate in the lips (74 of 784) against 0.8% in the cheeks (1 of 123) and 0.3% in the nasolabial folds (5 of 1,930), which is why the lips are excluded. It is not suitable during pregnancy or breastfeeding, over active skin infection, or for anyone who wants a filler that can be reversed. Patients with a history of keloid scarring or autoimmune disease need individual assessment, because both can alter the collagen response to the microspheres.
CaHA treatment questions answered
How much does CaHA cost in Singapore?
CaHA for contour is $1,400 per syringe. Diluted CaHA for skin tightening is $1,800 per session or $3,000 for 2 sessions. Prices are before GST.
How many syringes of CaHA do I need?
Most jawline, cheek or chin treatments use one to two syringes, depending on the length of jawline to be defined or the degree of chin projection needed. Diluted skin tightening is usually planned as 2 sessions, 4 to 8 weeks apart.
How long does CaHA treatment take?
CaHA treatment takes about 30 to 45 minutes, including numbing time for diluted treatment.
When will I see results?
Undiluted CaHA shows immediately, because the gel adds volume on the day. The firming from new collagen builds over two to three months.
Can CaHA be combined with HIFU on the same day?
Both can be performed on the same day, but I prefer HIFU first and diluted CaHA six weeks later, the sequence that gave the larger gain in elastin in a randomised study.
Is CaHA painful?
The CaHA used for contour contains lidocaine, and numbing cream is applied before diluted treatment. Most patients describe pressure rather than pain.
Is Radiesse good for the jawline?
Yes, and it is the area I use it for most. The decade review states that “Radiesse has a high G’ providing it with greater lifting capacity than many other dermal fillers” and that “Radiesse has one of the highest viscosities when compared with other dermal fillers. This allows it to remain in the place where it is injected and not to migrate into the surrounding tissue.” I place undiluted CaHA with lidocaine along the jawline, chin and cheek at $1,400 a syringe, and most faces need one to two syringes for the jawline.
Can Radiesse be used on the neck and for skin tightening?
Yes, in diluted form. The 50-patient case series “found that diluting and hyperdiluting Radiesse® with flexible dilution ratios favoured a treatment’s individualization, providing improved skin quality, elasticity, tightening, and firmness, without volume augmentation.” I use diluted CaHA on the lower face, neck, décolletage, hands and arms at $1,800 a session or $3,000 for two sessions. Use outside the face is off-label, and I explain this before treatment.
How many sessions of Radiesse do I need, and how often is it repeated?
Undiluted CaHA for contour is one session, with a top-up at 12 to 18 months. Diluted CaHA for skin tightening is two sessions four to eight weeks apart. The 2019 consensus describes “The characteristic of Radiesse of long-term collagen stimulation” and the nasolabial fold trial extension reported that “At least 30 months after the last Radiesse treatment, 40 percent of the folds evaluated remained improved.” I review at three months and plan maintenance from there.
Is Radiesse safe?
The 2019 consensus concludes that “Radiesse® (CaHA) is associated with a high and well-established safety profile and is a very effective agent for soft tissue augmentation of different face and body areas”, and the decade review notes that “In 2013, Radiesse reached a distribution milestone with more than five million syringes shipped for a variety of aesthetic indications without any safety concerns.” The main risks are nodules, which is why I do not use it in the lips, and vascular occlusion, which is why I inject slowly with a cannula where the anatomy calls for it. The full risk discussion is on my CaHA filler in Singapore review.
Do you offer Sculptra as well as Radiesse?
I offer both. The 2025 immunology review describes them as the two leading options. “Two of the most popular regenerative fillers are calcium hydroxylapatite (CaHA-CMC; Radiesse, Merz Aesthetics, Raleigh, NC) and poly-L-lactic acid (PLLA; Sculptra Aesthetics, Galderma, Dallas, TX).” On this page the plan is CaHA, which gives shape on the day and then builds collagen. PLLA suits a face that has lost thickness across a wide area and can wait three months for the result, and it is covered on my collagen biostimulator guide. The head-to-head comparison is in the FAQ on my CaHA filler in Singapore review.

Book a consultation with Dr Gerard Ee at The Clifford Clinic
Dr Gerard Ee consults and performs CaHA treatment at The Clifford Clinic, 50 Raffles Place, Singapore. Consultations are by appointment. Message the clinic on WhatsApp, or call 6532 2048.
Selected References
Published studies cited on this page
- Jacovella PF. Use of calcium hydroxylapatite (Radiesse) for facial augmentation. Clin Interv Aging. 2008;3(1):161–174. doi:10.2147/cia.s2065
- van Loghem J, Yutskovskaya YA, Werschler WP. Calcium hydroxylapatite, over a decade of clinical experience. J Clin Aesthet Dermatol. 2015;8(1):38–49.
- Goldie K, Peeters W, Alghoul M, et al. Global consensus guidelines for the injection of diluted and hyperdiluted calcium hydroxylapatite for skin tightening. Dermatol Surg. 2018;44 Suppl 1:S32–S41. doi:10.1097/DSS.0000000000001685
- de Almeida AT, Figueredo V, da Cunha ALG, et al. Consensus recommendations for the use of hyperdiluted calcium hydroxyapatite (Radiesse) as a face and body biostimulatory agent. Plast Reconstr Surg Glob Open. 2019;7(3):e2160. doi:10.1097/GOX.0000000000002160
- Massidda E. Starting point for protocols on the use of hyperdiluted calcium hydroxylapatite (Radiesse) for optimizing age-related biostimulation and rejuvenation of face, neck, décolletage and hands, a case series report. Clin Cosmet Investig Dermatol. 2023;16:3427–3439. doi:10.2147/CCID.S420068
- Doyle A, Looi I, Chu P. Microfocused ultrasound with visualization (MFU-V) and hyperdilute calcium hydroxylapatite (CaHA-CMC) of the lower face and submentum to treat skin laxity. Aesthet Surg J. 2024. doi:10.1093/asj/sjae226
- Yutskovskaya YA, Sergeeva AD, Kogan EA. Combination of calcium hydroxylapatite diluted with normal saline and microfocused ultrasound with visualization for skin tightening. J Drugs Dermatol. 2020;19(4):405–411. doi:10.36849/JDD.2020.4625
- Ramirez S, Puah IBK. Effectiveness of combined microfocused ultrasound with visualization and subdermal calcium hydroxyapatite injections for the management of brachial skin laxity. J Cosmet Dermatol. 2021;20:3871–3879. doi:10.1111/jocd.14573
- Goldberg DJ, Amin S, Hussain M. Acne scar correction using calcium hydroxylapatite in a carrier-based gel. J Cosmet Laser Ther. 2006;8:134–136. doi:10.1080/14764170600891632
- Casabona G. Combined use of microfocused ultrasound and a calcium hydroxylapatite dermal filler for treating atrophic acne scars, a pilot study. J Cosmet Laser Ther. 2018. doi:10.1080/14764172.2017.1406606
- Kadouch JA. Calcium hydroxylapatite, a review on safety and complications. J Cosmet Dermatol. 2017;16(2):152-161. doi:10.1111/jocd.12326
- Corduff N, Goldie K. The immunologic spectrum of biostimulators and its clinical importance. Plast Reconstr Surg Glob Open. 2025;13(8):e7001. doi:10.1097/GOX.0000000000007001
This page is written from published research and from clinical experience treating faces in Singapore since 2012. It is for general education, not medical advice. Suitability, likely result, downtime and risk can only be established at a consultation. Dr Gerard Ee provides the treatments described on this page at The Clifford Clinic.

