PDRN Skinboosters
Wrinkles, saggy skin and other signs of skin aging seem to be every women’s nightmare as they age. This explains why new anti-aging products are always being pushed out into the market to try to turn back the clock. However, the current focus is no longer on filling up new wrinkles but helping the skin heal and rejuvenate from within. This has led to the latest skin treatment craze originating from South Korea called PDRN Skinbooster – A skin treatment said to reverse signs of ageing and give the highly sought after ‘baby skin’ appearance. It is made from salmon DNA which is shown to be very similar to human DNA and hence is highly compatible with the human body. The salmon DNA is first purified and sterilised to remove any substances which can trigger an immune response in the body. It is then broken up into polydeoxyribonucleotides (PDRN) which play a key role in the anti-aging effect of the PDRN Skinbooster treatment.
How does it work?
PDRN activates the adenosine A2A receptors in the body. This causes an increase in the expression of vascular endothelial growth factor (VEGF) which is a type of growth factor that helps to stimulate the formation of new blood vessels. With more blood vessels, more blood can be brought to the area and this helps to improve skin repair and wound healing. This effect of PDRN is supported by a study which showed that blood flow greatly increased in skin flaps treated with PDRN. Furthermore, activating the adenosine A2A receptors also helps to reduce inflammation. It leads to a decrease in the production of inflammatory cytokines which are substances in the body that promote inflammation and causes an increase in the production of anti-inflammatory cytokines which are substances that help to reduce inflammation.
PDRN also increases the production of growth factors such as fibroblast growth factor (FGF) which stimulates the growth and activity of fibroblasts. Fibroblasts are cells that are required to regenerate important components of the skin such as collagen and glycosaminoglycans. Collagen is a protein that increases the strength and elasticity of the skin while glycosaminoglycans are molecules that improve hydration and moisture of the skin. Therefore, both play a major role in rejuvenating the skin and reducing signs of aging. The bad news is that the production of collagen and glycosaminoglycans decline with age, explaining the loss in moisture, elasticity and firmness of the skin. Therefore, it is no wonder that they are highly sought after today, which can be seen from the plethora of products ranging from collagen supplements to skincare products containing collagen or glycosaminoglycans. However, PDRN takes a different approach as instead of directly supplementing the skin with collagen or glycosaminoglycans, PDRN works by stimulating the skin to produce these important components to regenerate the skin from within.
Lastly, PDRN can be broken down by the body to generate nucleotides which are building blocks of DNA. These building blocks can then be used in DNA synthesis to form new DNA again. The increase in DNA synthesis stimulates cell growth and proliferation and hence leads to quicker tissue regeneration and wound healing. Furthermore, PDRN also helps protect cells from UV induced DNA damage. Exposure to ultraviolet radiation from the sun can damage DNA and cause premature signs of aging. PDRN helps to boost DNA repair and hence protects the skin from UV induced damage.
Is PDRN really that effective? The effectiveness of PDRN on healing and regeneration can be seen in the effects of PDRN on diabetic foot ulcers and skin graft donor sites. A study showed that the patient group treated with PDRN had nearly two times the rate of complete healing of difficult-to-heal diabetic foot ulcers. Furthermore, another study showed that administering PDRN decreased the healing times of skin graft donor sites. Therefore, it is no question that PDRN is a valuable substance for healing and regeneration and hence can be used to improve the aesthetic appearance of our skin. This explains why the PDRN Skinbooster treatment is rising in popularity due to its anti-aging properties and ability to revitalize the skin.
Benefits of PDRN Skinbooster on the aesthetic appearance of skin
- Increase skin elasticity (Study showed that skin elasticity increased by 21.78% after treatment)
- Increase skin hydration (Study showed that skin hydration increased by 14.69% after treatment)
- Reduce skin surface roughness
- Reduce skin pigmentation
- Reduce fine lines and wrinkle depth
- Skin normalization – Thickens and strengthens the skin to create a stronger defense barrier against factors that can cause premature aging of skin
- Improve skin tone and reduce pores
- Improve healing and reduce scar formation