Understanding Acne
Acne is a chronic and highly common skin condition that occurs when hair follicles become clogged with oil (sebum) and dead skin cells. This clogging process, often combined with bacteria and inflammation, leads to the formation of pimples, blackheads, and cysts.
Pimples and acne are the same condition. Whether you call it a pimple, a breakout or acne, what I treat is the same inflamed follicle, and the treatment depends on how deep and how inflamed it is rather than on the word used for it.
Teenage Acne
Adolescent acne is commonly triggered by hormonal fluctuations during puberty, leading to increased sebum production and clogged pores. During the teenage years, acne often presents as widespread breakouts with a mix of blackheads, whiteheads, and superficial pustules. In contrast to adult acne, teenage acne is often more responsive to standard topical and oral treatments and tends to resolve more quickly.
Adult Acne
Adult acne can manifest as persistent breakouts from adolescence, late-onset acne occurring for the first time in adulthood, or even recurrent acne after a period of clear skin. Unlike teenage acne, adult acne can be triggered by various factors, including hormonal imbalances, stress, certain medications, and lifestyle habits. While less common than teenage acne, adult acne can greatly impact one’s confidence and self-esteem.
Types of Acne and Pimples I Treat

Papules
Small, raised bumps on the skin that are often red and may feel tender to the touch. They indicate inflammation within the hair follicle.

Pustules
Small, inflamed bumps containing pus, sitting at the surface of an inflamed follicle. These are what most people mean by a pimple. They are not the same as whiteheads, which are closed comedones and are not inflamed.

Nodules
Larger, firm, and often painful bumps that develop deeper within the skin. They represent a more severe form of inflammation and can persist for weeks or months.

Cystic Lesions
Large, pus-filled, and often painful bumps that occur deep within the skin. They are the most severe form of acne and can often lead to scarring. Scarring that has already formed is addressed separately, as described in the acne scar treatment guide.
Causes of Acne
Acne often begins with an excess of sebum (oil) production by the skin’s glands. This excess oil can mix with dead skin cells and debris, leading to clogged pores. If these pores become blocked, blackheads or whiteheads may form.
These clogged pores also create an ideal environment for the bacteria involved in acne to thrive. As the bacteria multiply, your immune system reacts to the clogged and infected pores, resulting in redness, swelling, and pus-filled lesions.
Acne in both teenagers and adults can be exacerbated and triggered by:
- Hormonal Changes: Menstrual cycles, stress, and underlying hormonal imbalances (like PCOS) can increase sebum production, making the skin more susceptible to breakouts as androgens stimulate the oil glands.
- Genetics: A strong family history of acne suggests a genetic predisposition, meaning you are more likely to struggle with the condition if it runs in your family.
- Skincare and Makeup: Using heavy, oil-based, or pore-clogging (comedogenic) products can physically block hair follicles and exacerbate the formation of acne.
- Diet & Lifestyle: High sugar and greasy foods may lead to systemic inflammation and hormone fluctuations, while lack of sleep and chronic stress elevate cortisol levels, further promoting acne.
- Environmental Factors: External elements such as pollution, high humidity, and excessive sweating can create a breeding ground for bacteria and cause skin irritation, contributing to breakouts.
Why Treat Acne Early
Untreated or improperly managed acne can leave behind permanent physical and emotional marks. The intense inflammation can result in lasting consequences like severe scarring and stubborn post-inflammatory hyperpigmentation.
Hence, early intervention is critical, as treating acne promptly is the best defence against permanent textural damage, and it also helps to protect your long-term confidence.
Acne and Pimple Treatments I Use
Which treatment I reach for depends on the type of lesion, the severity, your skin type and any other condition affecting the skin. The list below is grouped by what the acne is doing, not by how new the technology is.
Comedonal acne: blackheads and whiteheads
- Topical Treatments: These treatments can help manage mild to moderate acne by potentially unclogging pores, reducing inflammation, and preventing the growth of the bacteria involved in acne. Examples include retinoids and antibacterial creams.
- AGNES RF, and sometimes AviClear: For comedonal acne I usually use AGNES RF, and I will consider AviClear as well depending on the skin and the spread of the lesions.
Papular and pustular acne
- Gold Photothermal Therapy (PTT): Gold nanoparticles are used to manage the bacteria involved in acne and sebaceous glands. Gold PTT could lead to long-term acne control and improvement in skin texture.
- Platinum Photothermal Therapy (PTT): Another treatment that employs platinum nanoparticles to address acne and control sebum production, Platinum PTT may be particularly helpful for individuals with inflammatory acne.
- AviClear: For papular acne AviClear is usually my choice. It is a 1726 nm laser aimed at the sebaceous gland, given as a course of sessions, and improvement can continue after the final session.
Nodular and cystic acne
- AGNES RF: For nodular and cystic acne this is usually what I use. AGNES RF passes radiofrequency energy through a fine insulated needle to treat individual sebaceous glands, which reduces oil production at the lesions treated. It is the option I reach for most often where lesions are deep and scarring is a concern.
- Isotretinoin: This oral medication helps treat severe or recalcitrant acne. Isotretinoin reduces sebum production, regulates skin cell turnover, and reduces inflammation. I prescribe it for severe acne that has not responded to other treatments.
Medication or a procedure?
Some people are treated with medication alone. That tends to be younger children and teenagers. Whether I add a procedure depends on the skin type, the severity of the acne, and any other condition affecting the skin — rough texture, for instance, may do better with a non-insulated microneedle fractional radiofrequency device such as Secret RF.
A procedure is not always appropriate for the type of acne in front of me. Where that is the case I will say so and treat the acne another way.
Secret RF as an add-on for active acne. For patients with rough skin texture and acne that is not yet controlled, I sometimes add Secret RF fractional microneedling to the medical plan. It is an add-on to the treatments above, not a replacement for them. Secret RF for acne is $1,500 per session before GST.
Supporting care for acne-prone skin
HydraFacial, chemical peels and LED light are part of some acne plans at my clinic, but as supporting care alongside medical treatment. HydraFacial clears blocked pores at the surface and helps congested, oily skin between medical treatments; on its own it will not cure acne. Chemical peels, $200 per session, help comedonal acne and the marks left after breakouts over a course of four to six sessions. Blue and red LED light has short-term randomised evidence in mild to moderate acne and I use it as an addition to a topical routine, not in place of one. None of the three replaces topicals, oral medication, isotretinoin or the devices above.
About Dr Gerard Ee
MBBS (UK), MRCS (Edinburgh), PGDip Practical Dermatology (Cardiff)
I earned my medical degree (MBBS) at St George’s University of London, and worked at Singapore General Hospital, the National University Hospital and Mount Sinai Hospital in New York before becoming a member of the Royal College of Surgeons of Edinburgh.
I trained in surgery to MRCS (Edinburgh) and hold a postgraduate diploma in practical dermatology from Cardiff University. I have practised aesthetic medicine for more than ten years, with a particular focus on acne, acne scarring and pigmentation. My aim at a consultation is that you leave understanding what is driving your acne and why a particular plan has been suggested.

Pimple Removal and Acne Treatment Options in Singapore
Acne is the focus
Doctor-led consultation
Medicine and procedures
Reviewed at one week
Adult Acne Treatment Cost in Singapore
| Treatment | Cost |
| Topical Treatments | From $150 |
| Gold Photothermal Therapy | $700 per session, or $3,500 for 5 sessions |
| Platinum Photothermal Therapy | $700 per session |
| AGNES RF | $800 to $1500 |
| AviClear | $1,800 per session |
| Isotretinoin | About $500 a month, depending on dose |
| Secret RF for active acne (add-on) | $1,500 per session |
| Chemical peel (supporting care) | $200 per session |
The final cost of treatment may vary based on the type and severity of your acne, the number of sessions required or the treatment duration. The full price list with course totals is on the acne treatment cost in Singapore page. Book a consultation today for a personalised quote.
Frequently Asked Questions About Acne Treatments in Singapore
Are acne treatments painful?
No, most modern acne and pimple treatments are designed to be minimally invasive, resulting in very little pain. While advanced procedures like lasers or deep peels may involve a mild stinging or heating sensation, these could be managed with numbing creams. This ensures your comfort is prioritised, making the overall experience easily tolerable.
Can adult acne be completely cured?
While there is no universal ‘cure’ that guarantees acne will never return, adult acne can certainly be managed and controlled long-term. By identifying and addressing the specific lifestyle or hormonal triggers, a personalised treatment plan could lead to sustained periods of clear skin.
What are the symptoms of adult acne?
You might notice inflammatory lesions such as papules, pustules, and nodules, often appearing around your chin, jawline, and neck. While blackheads and whiteheads can occur, they’re typically less common than in teenage acne. In some cases, you may also experience cystic acne, which involves deep and sometimes painful cysts. Come in for an assessment so the pattern can be identified properly.
What are the implications of adult acne?
Beyond the visible blemishes, adult acne can significantly impact your self-esteem and social life. Persistent or severe breakouts can also lead to scarring, a long-term concern for many. Getting treatment underway early gives the best chance of limiting scarring.
How long does it take to see results from acne treatment?
The timeline varies with the type and severity of your acne and the treatment we agree on:
- Topical Treatments: You may start noticing skin improvements within a few weeks of using topical treatments like retinoids or antibacterial creams.
- Laser Therapy: The results of laser therapy can be seen gradually over several sessions, with most individuals noticing improvement within a few months.
- Isotretinoin: Isotretinoin typically takes several months to show improvement in acne. You may notice initial dryness and some acne purging in the first few weeks, but the full effects usually become apparent after three to six months.
- AGNES RF: AGNES RF treatment often requires multiple sessions spaced a few weeks apart. You may see gradual improvement in your acne over time, with optimal results typically achieved after a series of treatments.
Can oral medications help treat adult acne?
Yes, oral medications can be effective for moderate to severe adult acne that hasn’t responded well to topical treatments. I may prescribe oral antibiotics to reduce inflammation, hormonal treatment for women whose acne is hormonally influenced, or isotretinoin for severe cases.
Important Considerations:
- Side Effects: Oral medications can have potential side effects, so it’s advisable to discuss these with the doctor before starting treatment.
- Antibiotic Resistance: Long-term use of antibiotics can lead to antibiotic resistance, so they are typically used for a limited duration.
- Pregnancy: Some oral medications, particularly Isotretinoin, can cause severe birth defects and should not be taken during pregnancy.
The doctor will consider your needs and medical history before recommending oral medications. He will also discuss the potential benefits and risks to help you make an informed decision about your acne and pimple treatment in Singapore.
Don’t let acne impact your confidence. Book a consultation with me at The Clifford Clinic to plan your acne treatment.
Is pimple removal the same as acne treatment?
Yes. Pimple removal and acne treatment describe the same work. A single inflamed lesion can be settled quickly with an injection or a light-based treatment, while recurring pimples need a plan that reduces oil production and stops new lesions forming.
What is the most effective acne treatment?
There is no single most effective treatment, because effectiveness depends on what is driving the acne. For comedonal acne, topical retinoids do most of the work. For inflammatory acne with a strong oil component, AGNES RF, AviClear or Gold PTT target the sebaceous gland directly. For severe nodular or cystic acne, isotretinoin remains the most reliable option. The treatment that works is the one matched to the type of acne in front of me.
What is the best treatment to stop acne coming back?
Stopping acne returning is a different job from clearing it. Clearance can be achieved with several treatments, but recurrence is governed by oil production and follicle behaviour, which is why maintenance matters more than the initial course. Treatments that reduce sebaceous gland activity, such as AGNES RF and AviClear, together with a maintenance topical, are what hold the result.
How do Koreans treat acne?
Korean practice treats earlier and more often. The pattern is lighter, more frequent in-clinic sessions rather than one aggressive course, combined with strict barrier care between them. AGNES RF, the device I use most for nodular and cystic acne, was developed in Korea, and its approach is characteristic of how Korean acne practice thinks: an insulated microneedle heats the sebaceous gland itself while sparing the skin surface, treating the gland that produces the problem rather than only the lesion sitting on top of it. I have used AGNES for twelve years and work the same way, treating consistently and early rather than waiting for acne to become severe.
This page is written from published research and from clinical experience in Singapore since 2012. It is for general education, not medical advice. Whether a treatment suits you, what it may achieve and what it may risk can only be established at a consultation. Dr Gerard Ee is the Medical Director of The Clifford Clinic, a private clinic in Singapore, and treatments discussed on this site are provided commercially.
What happens at an acne consultation
The first appointment is a history and an examination, not a sales conversation. What I ask about:
- When the acne first started
- Family history of acne
- Whether the periods are regular
- The type of acne and where it sits on the face or body
- What skincare and make-up products are being used
- Diet and sleep
What changes my recommendation most often is risk and family planning. If you are trying to conceive, or may be, say so before anything is prescribed.
How often I review acne treatment
Everyone is reviewed at one week. After that it depends on what you are on:
- Lasers — I see you every two weeks
- HydraFacial — monthly
At review what matters is how many new lesions are appearing, how many are painful, whether there are side effects, and whether the plan has actually been usable day to day. If it has not, tell me — adjusting it is easier than abandoning it.
Acne treatment in pregnancy and breastfeeding
If you are pregnant, think you may be, or are breastfeeding, tell me before anything is prescribed. The plan is built differently.
- Topical creams need to be changed. Several standard acne topicals are not suitable at these times.
- AGNES RF and AviClear are not done during pregnancy or breastfeeding.
- Isotretinoin causes severe birth defects and is not used in pregnancy.
There is more detail on acne and pregnancy.
Show the 8 references
- Reynolds RV, Yeung H, Cheng CE, et al. Guidelines of care for the management of acne vulgaris. J Am Acad Dermatol. 2024;90(5):1006.e1-1006.e30. PubMed 38300170
- Nast A, Al Wattar BH, Beylot Barry M, et al. Update of the EuroGuiDerm evidence-based guideline for the treatment of acne — short version. J Eur Acad Dermatol Venereol. 2026;40(7):1162-1172. PubMed 41847993
- Arowojolu AO, Gallo MF, Lopez LM, Grimes DA. Combined oral contraceptive pills for treatment of acne. Cochrane Database Syst Rev. 2012;2012(7):CD004425. PubMed 22786490
- Hebert A, Thiboutot D, Stein Gold L, et al. Efficacy and safety of topical clascoterone cream, 1%, for treatment in patients with facial acne: two phase 3 randomized clinical trials. JAMA Dermatol. 2020;156(6):621-630. PubMed 32320027
- Alexiades M, Kothare A, Goldberg D, et al. Novel 1726 nm laser demonstrates durable therapeutic outcomes and tolerability for moderate-to-severe acne across skin types. J Am Acad Dermatol. 2023;89(4):703-710. PubMed 37328000
- Ahn GR, Kim JM, Park SJ, et al. Selective sebaceous gland electrothermolysis using a single microneedle radiofrequency device for acne patients: a prospective randomized controlled study. Lasers Surg Med. 2020;52(5):396-401. PubMed 31502662
- National Institute for Health and Care Excellence. Acne vulgaris: management. NICE guideline NG198.
- Cutera. AviClear important safety information. Manufacturer safety information, not comparative efficacy evidence.
Acne consultations and treatment with Dr Gerard Ee take place at The Clifford Clinic, 50 Raffles Place, Singapore.
For more detail, read the separate guides to spironolactone, the contraceptive pill for acne and isotretinoin.
In this series: acne treatment in Singapore
Every page in the acne series, in the order I use them in clinic. Acne scars have their own series, starting from the acne scar treatment review.
Review and guides
- Acne Treatment in Singapore: A Complete Review of Every Treatment and Why Acne Comes Back
- Acne in Singapore: Types, Causes and When to See a Doctor
- The Acne Library
- Acne Treatment Cost in Singapore, Every Price Per Session and Per Course
- A Patient’s Acne Treatment Review: The Mothership Story
Treatments I use
- AGNES RF acne treatment
- AviClear laser acne treatment
- Gold PTT for acne
- Platinum PTT for acne
- Isotretinoin (Accutane): how it works and its side effects
- Hormonal acne treatment in Singapore
- Teenage acne treatment in Singapore
- Secret RF as an add-on for active acne
Comparisons and evidence
- AGNES vs AviClear vs Gold PTT
- Accure vs AviClear
- AviClear vs isotretinoin
- Spironolactone vs Accutane
- Why your AGNES acne treatment did not work
- Why AviClear did not work for you
- Does light therapy work for acne?
Supporting care

Book a consultation with Dr Gerard Ee at The Clifford Clinic
Dr Gerard Ee consults, prescribes and personally performs the procedures described on this page at The Clifford Clinic, 50 Raffles Place, Singapore. Consultations are by appointment. Message the clinic on WhatsApp, or call 6532 2048.



