Skin Booster vs Rejuran

Skin Booster vs Rejuran


With the anti-aging craze today, Rejuran and skin boosters are both highly sought-after treatment options to reverse the signs of aging and revitalize the skin. As the administration and effects of both skin treatments bear some similarities, there is some confusion between the two with people being unsure on which treatment they should get. This article aims to clear up any confusion between Rejuran and skin boosters and hopefully help you decide which one is more suited for your skin. Before comparing key differences between both skin treatment options, it is important to first have a basic understanding of how each treatment works and their potential benefits on the skin.


Introduction to Rejuran

Rejuran is a skin treatment which is said to reverse aging and rejuvenate the skin to give the highly sought after ‘baby skin’ appearance. It is made from salmon DNA which is shown to be very similar to human DNA and hence is safe and compatible to be used on the human body. The salmon DNA is first purified and sterilized to remove any substances which can trigger an immune response in the body. It is then broken up into polydeoxyribonucleotides (PDRN) which play a key role in the anti-aging effect of the Rejuran treatment.


How does it work?

By activating the adenosine A2A receptors in the body, PDRN brings about a few effects:

  1. Increased expression of vascular endothelial growth factor (VEGF) which is a substance that helps to stimulate the formation of new blood vessels. With more blood vessels, more blood can be brought to the area, helping to improve skin repair and wound healing.
  2. Reduce inflammation by decreasing the production of pro-inflammatory substances and increasing the production of anti-inflammatory substances in the body.
  3. Increase the growth and activity of fibroblasts which are cells in the skin required to regenerate important components such as collagen and glycosaminoglycans. Collagen is a protein that increases the strength and elasticity of the skin while glycosaminoglycans such as hyaluronic acid improves hydration. Therefore, both play a major role in rejuvenating the skin and reducing signs of aging.


Lastly, PDRN can be broken down by the body to generate nucleotides which are building blocks of DNA. These building blocks can then be used to form new DNA again. The increase in DNA synthesis stimulates cell growth and proliferation and hence leads to quicker tissue regeneration and wound healing.


Benefits of Rejuran on the aesthetic appearance of skin

– Increase skin elasticity (Study showed that skin elasticity increased by 21.78% after treatment)

– Increase skin hydration (Study showed that skin hydration increased by 14.69% after treatment)

– Reduce skin surface roughness

– Reduce skin pigmentation and scars

– Reduce fine lines and wrinkle depth

– Skin normalization – Thickens and strengthens the skin to create a stronger defense barrier against factors that can cause premature aging

– Improve skin tone and reduce pores


Introduction to Skin Boosters and how it works

Skin boosters are filler treatments mainly containing a substance called hyaluronic acid which is a natural component of our skin. It involves micro-injections of a hyaluronic acid filler to improve hydration and achieve youthful, radiant and brighter looking skin. How does injecting hyaluronic acid achieve this? Firstly, hyaluronic acid has the amazing ability to bind and retain water up to 1000 times its own weight, greatly increasing the amount of moisture within the skin. The increased hydration then causes the skin to look radiant, plumper and more youthful.

Furthermore, the benefits of hyaluronic acid are not simply limited to hydration as it also helps to:

– Promote collagen production

– Stimulate would healing

– Increase elasticity of the skin

– Reduce inflammation

– Has anti-oxidative effects


Benefits of Skin Boosters on the aesthetic appearance of skin

Therefore, this explains why skin booster treatments which contain hyaluronic acid can translate to many visible benefits to the skin and is a highly sought-after filler treatment today. The benefits of the treatment are:

– Increase in skin brightness

– Increase in skin hydration

– Increase in skin elasticity

– Reduction in skin surface roughness

– Reduction of fine lines and wrinkles

– Improvement of acne scars



Skin Boosters vs Rejuran

After learning about how each treatment works and their benefits to the skin, we can now delve into the differences between Rejuran and skin boosters and the key features that set both treatment options apart.

How they work:

With age, there is a loss of important components of the skin such as hyaluronic acid and collagen, leading to a loss of moisture, elasticity and firmness of the skin. This explains the common signs of skin aging such as dull, dry skin with increased wrinkle formation. Both Rejuran and skin boosters tackle this problem of skin aging but greatly differ in their approach towards achieving more youthful looking skin.

As discussed earlier, skin boosters are filler treatments which involve micro-injections of hyaluronic acid into the skin to restore hydration and achieve brighter skin with reduction of fine lines. Therefore, skin boosters directly supplement the skin with hyaluronic acid to increase its levels and reduce signs of aging. However, Rejuran acts on a cellular level to promote tissue regeneration, wound healing and skin repair. Instead of directly supplementing the skin with important components such as hyaluronic acid, it stimulates the skin to produce these components on its own, regenerating the skin from within. Furthermore, a study comparing Rejuran with skin boosters showed that Rejuran causes more fibroblast activity and hence leads to greater collagen production and anti-aging effects.

Best suited for:

As skin boosters mainly focus on improving hydration of the skin, it is best suited for people with extremely dry skin and those who want to reduce the appearance of their fine lines and wrinkles.

On the other hand, Rejuran is best suited for people with severely damaged and aging skin as it focuses on skin repair and regeneration. It is also not limited to the older age group with signs of skin aging but extends to people suffering from acne scarred skin as well. Rejuran can smoothen the skin, improve healing and help to reduce the appearance of acne scars. Furthermore, people with large pores and oily skin can also greatly benefit from the Rejuran treatment.

Treatment process and side effects:

Both involve injections of the product into the skin. With skin boosters, it can be administered via an injector gun or manually with a small needle. Similarly, for Rejuran, a fine needle is used to administer small amounts of the product under the skin. The recommended treatment plan for skin boosters is for the first 3 treatments to be done 4 weeks apart and any subsequent treatments to be done every 6 months. The recommended treatment plan for Rejuran is for the first 4 treatments to be done 2-4 weeks apart and any subsequent treatments to be done every 6 months.

As for side effects, both can cause temporary injection related redness, swelling, bruising and appearance of small bumps which will eventually resolve.

It is also important to consult your dermatologist beforehand if you have done any other skin treatments and fillers as they may cross react with the Rejuran treatment.


In conclusion, Rejuran and skin boosters are 2 separate skin treatments which act in very different ways to rejuvenate the skin and turn back the clock to reduce signs of aging. Furthermore, the effects of both treatments with regards to anti-aging also differ as Rejuran takes on a more aggressive approach to anti-aging, promoting skin regeneration and repair. Which treatment option to choose depends on your skin condition and the anti-aging effect you are looking out for. It is also possible to combine both treatments together. Before deciding, it is important to consult and discuss with your dermatologist.